Given that India is celebrating her 75 years of independence (Azadi ka Amrit Mahotsav), a dialogue on India’s strategy for the next 25 years with regard to its science & technology environment is imperative to pre-empt challenges and capitalize on opportunities that lay ahead. In addition to anticipating contemporary developmental challenges, this dialogue provided fresh insight on S&T priorities, policy decisions and discussed the likely roadmap for the next 25 years of India’s S&T environment.